Manganese is an antioxidant necessary for the production of energy, and the blood breakdown of amino acids. It is essential for the metabolism of vitamin B-1 and E. It activates enzymes for proper digestion, helps to break down fats and cholesterol, helps to produce reproductive hormones, and nourishes the nerves, brain and skeletal system. It is used to help maintain healthy skin, bone and cartilage, as well as for glucose tolerance in diabetes, and osteoporosis.